Field of study: Biophysics
Topics of doctoral theses (supervisor)
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Study of electrochemical properties of of synthetic oligonucleotides and DNA modified with redox-active moieties –
graduate 2015
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Osmium tetroxide complexes as electroactive markers for DNA and their analytical utilization –
graduate 2007
Field of study: Genomics and Proteomics
Topics of doctoral theses (supervisor)
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Značení DNA elektroaktivními skupinami a fluorofory pro studium strukturních změn nukleových kyselin a detekci patogenů –
ongoing study
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A study of the formation of alternative DNA structures using electrochemical methods –
ongoing study
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New possibilities of sequence- and structure-specific analysis of DNA and RNA and their chemical modification using electrochemical methods –
graduate 2024
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Electrochemical methods for the monitoring of enzymatic reactions based on electroactivity of unmodified and modified DNA and on application of marker substrates –
graduate 2024
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Behavior of alternative DNA structures at electrically charged surfaces –
graduate 2023
Topics of doctoral theses (consultant)
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Interactions of p53 protein with guanine quadruplexes and other DNA secondary structures –
graduate 2022
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Influence of DNA topology on p53 binding –
graduate 2020
Field of study: Genomics and Proteomics
Topics of doctoral theses (supervisor)
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Novel methods of p53 protein-DNA interaction studies based on chemical modification, fluorescence and electrochemical analysis –
graduate 2018
Topics of doctoral theses (consultant)
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Novel approaches towards electroanalysis of natural and modified DNAs and their interactions –
graduate 2018
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DNA labelling with electrochemically active groups and luminophores for the analysis of nucleotide sequences –
graduate 2016
Field of study: Molecular and Cellular Biology
Topics of doctoral theses (supervisor)
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Electrochemical methods for detection of DNA-protein interactions and for monitoring of DNA enzymatic processing –
graduate 2018
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Construction of chemically modified nucleic acids for application in electrochemical DNA sensors –
graduate 2018
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Electrochemical biosensors for analysis of nucleotide sequences and DNA-protein interactions –
graduate 2016
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Interactions of p53 protein with DNA: influence of DNA structure-modulating agents, salt concentration and application of electrochemical methods in protein-DNA interaction studies –
graduate 2015
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Structure-specific binding of protein p53, its mutant forms and homologues to DNA –
graduate 2012
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Recent approaches in electrochemical analysis of damage, hybridization and interactions of DNA –
graduate 2009
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Interaction of tumor suppressor protein p53 and its homologs with specific DNA structures –
graduate 2006
Detailed information on doctoral topics and students